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Structure of 1020743-28-5
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4-Bromoquinoline-8-carbonitrile features a fused quinoline scaffold with bromine at the 4-position and a nitrile group at the 8-position, enabling diverse cross-coupling transformations. This electron-deficient heteroaromatic system integrates readily into pharmaceutical scaffolds and advanced materials, offering high stability under standard conditions and compatibility with palladium-catalyzed reactions.
4-Bromoquinoline-8-carbonitrile serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its compatible bromo and nitrile functionalities. The quinoline scaffold provides a rigid, planar framework ideal for constructing heterocyclic libraries and pharmaceutical intermediates. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling protocols, including Suzuki-Miyaura and Buchwald-Hartwig reactions, offering predictable reactivity for medicinal chemistry and materials science applications.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: