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CS-W001157 4
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3H-Imidazo[4,5-b]pyridine-5-carboxylic acid

  • CAS No. 1019108-05-4

  • Cat. No. CS-W021931
  • Purity≥97%
  • MDL No.MFCD09863858

*For research and further manufacturing use only, not for direct human use.

3H-Imidazo[4,5-b]pyridine-5-carboxylic acid|CS-W021931

Structure of 1019108-05-4

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General Information

  • CAS No. 1019108-05-4
  • Cat. No. CS-W021931
  • Purity ≥97%
  • MDL No. MFCD09863858
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight None
  • Synonym(s) 1H-Imidazo[4,5-b]pyridine-5-carboxylic acid
  • SMILES OC(=O)C1=NC2=C(C=C1)N=CN2

Description

3H-Imidazo[4,5-b]pyridine-5-carboxylic acid is a heterocyclic carboxylic acid featuring a fused imidazo-pyridine core with enhanced stability and solubility in polar solvents. This scaffold integrates readily into bioactive molecule design, offering a rigid, electron-deficient platform for medicinal chemistry applications.

Application

3H-Imidazo[4,5-b]pyridine-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused imidazopyridine core exhibits robust bench stability and facilitates efficient functionalization at the carboxylic acid terminus. The molecule functions as a key scaffold in the synthesis of kinase inhibitors and other bioactive compounds, enabling direct coupling reactions with amines, alcohols, and nucleophiles under standard conditions.

Safety Information

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Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.6561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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