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Structure of 1017793-21-3
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4-Bromo-3-chloro-2-fluoropyridine is a halogenated pyridine derivative featuring strategically positioned bromo, chloro, and fluoro substituents. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions and serves as a key scaffold for medicinal chemistry libraries. The orthogonal reactivity of its halogens permits sequential derivatization under mild conditions.
4-Bromo-3-chloro-2-fluoropyridine serves as a versatile trifunctional pyridine building block for medicinal chemistry and catalytic cross-coupling applications. Its orthogonal halogen reactivity enables sequential functionalization via Pd-catalyzed coupling, while the electron-deficient pyridine core enhances stability and facilitates nucleophilic substitution. Bench-stable and amenable to purification by distillation or flash chromatography, it functions reliably in the construction of complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: