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Structure of 1017540-91-8
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Methyl 2-{3-azaspiro[5.5]undecan-9-yl}acetate hydrochloride features a rigid, polycyclic amine scaffold that enhances metabolic stability and bioavailability. The protonated nitrogen improves solubility in aqueous systems, while the ester functionality enables straightforward derivatization. This compound serves as a key intermediate in medicinal chemistry for accessing structurally complex alkaloid analogs and constrained peptide mimetics.
Methyl 2-{3-azaspiro[5.5]undecan-9-yl}acetate hydrochloride serves as a versatile building block for spirocyclic alkaloid analogs and medicinal chemistry libraries. The tertiary amine functionality enables efficient salt formation, enhancing solubility and crystallinity for purification. Its ester group facilitates selective transformations, including reduction to the alcohol or hydrolysis to the carboxylic acid, while maintaining structural integrity under standard synthetic conditions. This compound functions as a key intermediate in the synthesis of complex nitrogen-containing scaffolds relevant to CNS-targeted drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: