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CS-W001157 4
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3-(4-Amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione

  • CAS No. 2304753-42-0

  • Cat. No. CS-0611556
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(4-Amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione|CS-0611556

Structure of 2304753-42-0

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General Information

  • CAS No. 2304753-42-0
  • Cat. No. CS-0611556
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₄N₄O₃
  • Molecular Weight 274.28
  • Synonym(s) None
  • SMILES O=C(C(N1C2=CC=CC(N)=C2N(C)C1=O)CC3)NC3=O

Description

This piperidine-2,6-dione scaffold features a fused benzimidazolone ring with a key amino-methyl substituent, delivering enhanced solubility and stability under standard conditions. The electron-rich heterocycle facilitates efficient coupling reactions in synthetic workflows.

Application

3-(4-Amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione serves as a versatile scaffold for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds. The benzoimidazolone core provides robust stability and hydrogen-bonding capacity, while the piperidinedione moiety offers dual carbonyl handles for derivatization. This compound functions as a key building block in the synthesis of fused heterocycles and exhibits favorable solubility and bench stability under standard laboratory conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   99.12
  • LogP   -0.1001
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   1

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