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Structure of 1016233-08-1
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tert-Butyl 3,3-bis(hydroxymethyl)azetidine-1-carboxylate features a strained azetidine core bearing two hydroxymethyl groups and a robust tert-butyl ester. This configuration enables selective functionalization under mild conditions, offering enhanced stability and solubility in polar organic media for synthetic applications.
tert-Butyl 3,3-bis(hydroxymethyl)azetidine-1-carboxylate serves as a versatile building block for the synthesis of constrained azetidine-containing scaffolds. The dual hydroxymethyl groups enable sequential functionalization or protection strategies, while the tert-butyl carbamate offers orthogonal stability and ease of removal under mild acidic conditions. This compound facilitates the construction of complex heterocycles and bioactive molecules through established coupling and cyclization protocols, demonstrating robust bench stability and compatibility with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: