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Structure of 3185-99-7
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1-Methyl-4-(methylsulfonyl)benzene features a methylsulfonyl group that imparts strong electron-withdrawing character and enhanced solubility in polar solvents. This bench-stable aromatic compound integrates readily into synthetic routes requiring stable, functionalized aryl building blocks. The para-substitution pattern ensures minimal steric interference during coupling reactions.
1-Methyl-4-(methylsulfonyl)benzene serves as a versatile aryl building block in medicinal chemistry and process development, offering a stable, bench-ready platform for Suzuki-Miyaura and other cross-coupling reactions. The methylsulfonyl group provides excellent electron-withdrawing character and functional group tolerance, enabling efficient derivatization while maintaining structural integrity during purification and scale-up.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: