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Structure of 1000524-74-2
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This difluoromethyl-substituted phenylacetic acid features a para-difluoromethyl group that imparts enhanced metabolic stability and lipophilicity. The carboxylic acid functionality enables direct conjugation or derivatization in synthetic routes. Its electron-withdrawing fluorine atoms modulate reactivity, making it valuable for medicinal chemistry applications requiring controlled release or targeted bioavailability.
2-[4-(Difluoromethyl)phenyl]acetic acid serves as a valuable building block for bioactive heterocycles and pharmaceutical scaffolds, enabling efficient incorporation of a difluoromethyl group adjacent to an aromatic ring. Its stability under standard synthetic conditions and compatibility with diverse coupling reactions facilitate straightforward functionalization. The molecule functions as a versatile intermediate in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: