Fmoc-D-Pro-L-Pro-OH

Name: Fmoc-D-Pro-L-Pro-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. None
Cat. No. CS-1269346
Purity≥97%
MDL No.None

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Fmoc-D-Pro-L-Pro-OH is a dipeptide building block featuring a fluorenylmethoxy carbonyl (Fmoc) group at the N-terminus and a proline residue in both D- and L-configurations. This configuration imparts conformational rigidity, enhancing structural stability during solid-phase peptide synthesis. The Fmoc moiety enables orthogonal protection, facilitating selective deprotection under mild basic conditions. Ideal for incorporating constrained Pro-Pro motifs into bioactive peptides, this derivative supports efficient coupling and high yields in sequence assembly workflows.

Application

Fmoc-D-Pro-L-Pro-OH serves as a valuable dipeptide building block for solid-phase peptide synthesis, enabling the efficient construction of proline-rich sequences and constrained peptide scaffolds. The Fmoc group provides orthogonal protection for the N-terminus, allowing selective deprotection under mild basic conditions. The D-Pro-L-Pro motif offers enhanced conformational rigidity and proteolytic stability, making it particularly useful in peptidomimetic design and bioactive peptide synthesis.

General Information

CAS No. None
Cat. No. CS-1269346
Purity ≥97%
MDL No. None
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₅H₂₆N₂O₅
Molecular Weight 434.48
Synonym(s) None
SMILES O=C(N1[C@@H](CCC1)C(O)=O)[C@@H]2N(C(OCC3C4=CC=CC=C4C5=CC=CC=C35)=O)CCC2

Computational Chemistry Data

TPSA N/A
LogP N/A
H_Acceptors N/A
H_Donors N/A
Rotatable_Bonds N/A

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Key Words

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Fmoc-D-Pro-L-Pro-OH

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