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CS-W001157 4
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(S)-2-Amino-3-cyclopentylpropionic acid

  • CAS No. 99295-82-6

  • Cat. No. CS-W008898
  • Purity≥98%
  • MDL No.MFCD01632069

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3-cyclopentylpropionic acid|CS-W008898

Structure of 99295-82-6

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General Information

  • CAS No. 99295-82-6
  • Cat. No. CS-W008898
  • Purity ≥98%
  • MDL No. MFCD01632069
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₂
  • Molecular Weight 157.21
  • Synonym(s) (S)-2-Amino-3-cyclopentylpropionic acid; 3-Cyclopentane-L-alanine
  • SMILES O=C(O)[C@@H](N)CC1CCCC1

Description

(S)-2-Amino-3-cyclopentylpropionic acid is a chiral non-proteinogenic amino acid featuring a cyclopentyl group that imparts enhanced lipophilicity and conformational rigidity. This structural motif supports its utility in peptide-based drug discovery, where it modulates receptor binding affinity and metabolic stability. The stereochemistry at the alpha carbon ensures precise interaction with biological targets.

Application

(S)-2-Amino-3-cyclopentylpropionic acid serves as a stereochemically defined building block for bioactive peptide synthesis, offering a rigid cyclopentyl moiety that modulates conformational preferences in peptidomimetics. Its well-established stability and compatibility with standard coupling protocols facilitate efficient incorporation into complex molecular architectures. Functions effectively as a structural analog in CNS-targeted compound development, particularly where enhanced metabolic stability and target selectivity are required.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.9786
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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