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CS-W001157 4
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Acetylleucine

  • CAS No. 99-15-0

  • Cat. No. CS-4647
  • Purity≥98%
  • MDL No.MFCD00026498

*For research and further manufacturing use only, not for direct human use.

Acetylleucine|CS-4647

Structure of 99-15-0

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General Information

  • CAS No. 99-15-0
  • Cat. No. CS-4647
  • Purity ≥98%
  • MDL No. MFCD00026498
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₃
  • Molecular Weight 173.21
  • Synonym(s) N-Acetyl-DL-leucine
  • SMILES CC(C)CC(C(O)=O)NC(C)=O

Description

Acetylleucine features a protected leucine side chain, enabling stable incorporation into peptide synthesis workflows. The acetyl group enhances solubility and reduces racemization risk during coupling steps. This derivative serves as a valuable building block for N-terminal modification in bioactive peptide sequences.

Synthesis

  • Route1

    References

    • Hirai, Kenji; Fujita, Makoto; Fuchikami, Takamasa Journal of Organometallic Chemistry, 1985 , vol. 279, p. 203 - 214
  • Route2

    References

    • Hirai, Kenji; Takahashi, Yoshitaka; Ojima, Iwao Tetrahedron Letters, 1982 , vol. 23, # 24 p. 2491 - 2494
  • Route3
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    • In-stock
      Acetylleucine|CS-4647
      99-15-0

    References

    • Lin, J.J.; Knifton, John F. Journal of Organometallic Chemistry, 1991 , vol. 417, # 1/2 p. 99 - 110

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   0.6218
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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