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CS-W001157 4
Total: USD 88.00

(2S,3S)-2-Acetamido-3-methylpentanoic acid

  • CAS No. 3077-46-1

  • Cat. No. CS-W017551
  • Purity≥96%
  • MDL No.MFCD00066072

*For research and further manufacturing use only, not for direct human use.

(2S,3S)-2-Acetamido-3-methylpentanoic acid|CS-W017551

Structure of 3077-46-1

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General Information

  • CAS No. 3077-46-1
  • Cat. No. CS-W017551
  • Purity ≥96%
  • MDL No. MFCD00066072
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₃
  • Molecular Weight 173.21
  • Synonym(s) None
  • SMILES CC[C@H](C)[C@@H](C(O)=O)NC(C)=O

Description

(2S,3S)-2-Acetamido-3-methylpentanoic acid is a chiral amino acid derivative featuring a sterically hindered side chain and a bench-stable acetamido group. This configuration enables precise incorporation into peptide scaffolds, where the methyl substitution enhances metabolic stability and modulates conformational flexibility in bioactive sequences.

Application

(2S,3S)-2-Acetamido-3-methylpentanoic acid serves as a stereochemically defined building block for β-amino acid derivatives and peptidomimetics. Its well-defined chiral centers enable reliable incorporation into complex scaffolds, while the acetamido and carboxylic acid functionalities offer direct handles for coupling reactions. The molecule exhibits bench stability and facilitates efficient purification, making it suitable for use in medicinal chemistry campaigns requiring precise stereocontrol and functional group compatibility.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   0.6218
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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