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CS-W001157 4
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Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate

  • CAS No. 98642-15-0

  • Cat. No. CS-0154398
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate|CS-0154398

Structure of 98642-15-0

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Description

Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate serves as a stable, moisture-tolerant protecting group for diol functionalities. This bifunctional reagent integrates seamlessly into complex molecule synthesis, enabling selective protection under mild conditions. The tert-butyl carbamate moieties offer robust stability while the hydroxypropane backbone provides strategic spatial positioning for downstream transformations.

Application

Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate serves as a stable, bench-ready protecting group for vicinal diols and amino-alcohols. It facilitates selective protection in complex molecule synthesis, enabling orthogonal deprotection strategies. The molecule exhibits excellent functional group tolerance and simplifies purification due to its high stability under standard reaction conditions.

General Information

  • CAS No. 98642-15-0
  • Cat. No. CS-0154398
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₆N₂O₅
  • Molecular Weight 290.36
  • Synonym(s) tert-butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate
  • SMILES CC(C)(OC(NCC(O)CNC(OC(C)(C)C)=O)=O)C

Computational Chemistry Data

  • TPSA   96.89
  • LogP   1.3967
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   4

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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