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Structure of 144912-84-5
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tert-Butyl (3-amino-2-hydroxypropyl)carbamate features a bifunctional side chain bearing both a primary amine and a hydroxyl group, enabling selective derivatization in peptide synthesis. The tert-butyl carbamate moiety provides stable protection under standard conditions while permitting mild deprotection with acid. This combination supports efficient incorporation into complex molecular architectures.
tert-Butyl (3-amino-2-hydroxypropyl)carbamate serves as a versatile bifunctional building block in synthetic organic chemistry, enabling the concurrent introduction of both amino and hydroxyl functionalities under mild conditions. The tert-butoxycarbonyl (Boc) group provides robust protection for the amine, allowing orthogonal deprotection in acidic or hydrogenolytic conditions. Its hydroxyl moiety supports derivatization via esterification or ether formation, while maintaining compatibility with standard coupling and functional group manipulation protocols. This stability and reactivity profile makes it particularly useful in peptide synthesis, carbohydrate chemistry, and the construction of complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07,GHS05
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: