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CS-W001157 4
Total: USD 88.00

tert-Butyl (3-amino-2-hydroxypropyl)carbamate

  • CAS No. 144912-84-5

  • Cat. No. CS-0037654
  • Purity≥95%
  • MDL No.MFCD04118107
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3-amino-2-hydroxypropyl)carbamate|CS-0037654

Structure of 144912-84-5

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Description

tert-Butyl (3-amino-2-hydroxypropyl)carbamate features a bifunctional side chain bearing both a primary amine and a hydroxyl group, enabling selective derivatization in peptide synthesis. The tert-butyl carbamate moiety provides stable protection under standard conditions while permitting mild deprotection with acid. This combination supports efficient incorporation into complex molecular architectures.

Application

tert-Butyl (3-amino-2-hydroxypropyl)carbamate serves as a versatile bifunctional building block in synthetic organic chemistry, enabling the concurrent introduction of both amino and hydroxyl functionalities under mild conditions. The tert-butoxycarbonyl (Boc) group provides robust protection for the amine, allowing orthogonal deprotection in acidic or hydrogenolytic conditions. Its hydroxyl moiety supports derivatization via esterification or ether formation, while maintaining compatibility with standard coupling and functional group manipulation protocols. This stability and reactivity profile makes it particularly useful in peptide synthesis, carbohydrate chemistry, and the construction of complex heterocyclic scaffolds.

General Information

  • CAS No. 144912-84-5
  • Cat. No. CS-0037654
  • Purity ≥95%
  • MDL No. MFCD04118107
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈N₂O₃
  • Molecular Weight None
  • Synonym(s) Tert-butyl n-(3-amino-2-hydroxypropyl)carbamate
  • SMILES CC(C)(C)OC(=O)NCC(CN)O

Computational Chemistry Data

  • TPSA   84.58
  • LogP   -0.1693
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P403+P233-P405-P501

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