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CS-W001157 4
Total: USD 88.00

4-(Dimethylamino)-2-butenoic acid

  • CAS No. 98548-82-4

  • Cat. No. CS-0782909
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Dimethylamino)-2-butenoic acid|CS-0782909

Structure of 98548-82-4

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General Information

  • CAS No. 98548-82-4
  • Cat. No. CS-0782909
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) None
  • SMILES O=C(O)/C=C/CN(C)C

Description

4-(Dimethylamino)-2-butenoic acid features a conjugated enoic acid scaffold bearing a dimethylamino group that enhances electron density at the β-position. This structural motif enables facile participation in Michael additions and facilitates coupling reactions under mild conditions. The molecule exhibits improved solubility in polar organic solvents, supporting its use in synthetic peptide modifications and bioconjugation workflows.

Application

4-(Dimethylamino)-2-butenoic acid serves as a versatile building block for synthesizing bioactive heterocycles and functionalized alkenes. Its conjugated enoic acid moiety enables reliable Michael additions, Diels-Alder reactions, and palladium-catalyzed couplings. The dimethylamino group enhances electron density for nucleophilic transformations while maintaining bench stability and compatibility with common protecting groups. This compound facilitates efficient access to substituted pyrrolidines and other nitrogen-containing scaffolds relevant to medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.1888
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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