Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-(Dimethylamino)but-2-enoic acid hydrochloride

  • CAS No. 98548-81-3

  • Cat. No. CS-0132058
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Dimethylamino)but-2-enoic acid hydrochloride|CS-0132058

Structure of 98548-81-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 98548-81-3
  • Cat. No. CS-0132058
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₂
  • Molecular Weight 165.62
  • Synonym(s) 4-(DIMETHYLAMINO)-2-BUTENOIC ACID HYDROCHLORIDE
  • SMILES O=C(O)/C=C/CN(C)C.[H]Cl

Description

4-(Dimethylamino)but-2-enoic acid hydrochloride features a conjugated enoic acid scaffold with a strongly electron-donating dimethylamino group, enhancing resonance stabilization. This bench-stable salt facilitates direct incorporation into peptide couplings and serves as a key building block for bioactive heterocycles and functional polymers under standard conditions.

Application

4-(Dimethylamino)but-2-enoic acid hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyrrolidines and other nitrogen-containing heterocycles via Michael addition or cyclization reactions. The conjugated enoate system exhibits high reactivity toward nucleophiles, while the dimethylamino group enhances electron density at the β-position. Its hydrochloride salt form provides improved bench stability and ease of handling, facilitating purification and incorporation into multi-step syntheses.

Synthesis

  • Route1
    • Methyl (E)-4-(dimethylamino)but-2-enoate hydrochloride|CS-0939890
      1259519-60-2
    • ~%
    • In-stock
      4-(Dimethylamino)but-2-enoic acid hydrochloride|CS-0132058
      98548-81-3

    References

    • Wyeth Patent: US2003/50222 A1, 2003 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.6106
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 98548-81-3 sigma98548-81-3 manufacturer98548-81-3 price98548-81-3 structure98548-81-3 SDSbuy 98548-81-398548-81-3 supplier98548-81-3 uses98548-81-3 molecular weightprice of 98548-81-398548-81-3 chemical name formula of 98548-81-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label