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Structure of 98349-25-8
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Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate is a bench-stable, moisture-tolerant quinolone core featuring electron-deficient fluorine substituents at C6 and C7. This structural motif enables direct incorporation into synthetic routes for fluoroquinolone antibiotics, offering enhanced metabolic stability and improved membrane permeability.
Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate serves as a key intermediate in the synthesis of fluoroquinolone-based scaffolds. Its difluorinated quinoline core enables enhanced metabolic stability and membrane penetration, while the ethyl ester group facilitates downstream functionalization via hydrolysis or coupling reactions. The cyclopropyl substitution at N1 provides steric and electronic tuning beneficial for antibiotic potency. Bench-stable and readily purified by flash chromatography, it functions reliably in standard synthetic workflows targeting bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: