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CS-W001157 4
Total: USD 88.00

2-Thiophenecarboxaldehyde

  • CAS No. 98-03-3

  • Cat. No. CS-W013657
  • Purity≥97%
  • MDL No.MFCD00005429

*For research and further manufacturing use only, not for direct human use.

2-Thiophenecarboxaldehyde|CS-W013657

Structure of 98-03-3

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General Information

  • CAS No. 98-03-3
  • Cat. No. CS-W013657
  • Purity ≥97%
  • MDL No. MFCD00005429
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄OS
  • Molecular Weight 112.15
  • Synonym(s) Thiophene-2-carboxaldehyde
  • SMILES O=CC1=CC=CS1

Description

trans-2-undecenal is mainly formed due to the oxidation of triolein while heating. It occurs naturally in coriander, fresh red pepper and watermelon.

Application

2-Thiophenecarboxaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thiophene-based scaffolds via Ullmann, Suzuki-Miyaura, and Mannich-type reactions. Its aldehyde functionality exhibits excellent compatibility with diverse functional groups, facilitating straightforward derivatization for medicinal chemistry applications. Bench-stable and readily purified by distillation, it functions reliably in standard synthetic workflows requiring precise regiocontrol and high reactivity.

Synthesis

  • Route1
    • In-stock
      2-Iodothiophene|CS-W007589
      3437-95-4
    • null|null
      201230-82-2
    • ~90%
    • In-stock
      2-Thiophenecarboxaldehyde|CS-W013657
      98-03-3

    References

    • Jiang, Jianwen; Wang, Pingping; Cai, Mingzhong Journal of Chemical Research, 2014 , vol. 38, # 4 p. 218 - 222
  • Route2
    • null|null
      5271-67-0
    • ~95%
    • In-stock
      2-Thiophenecarboxaldehyde|CS-W013657
      98-03-3

    References

    • Le Menez, Patrick; Hamze, Abdallah; Provot, Olivier; Brion, Jean-Daniel; Alami, Mouad Synlett, 2010 , # 7 p. 1101 - 1103
  • Route3
    • Thiophene-2-carbaldehydeoxime|CS-0171538
      29683-84-9
    • ~96%
    • In-stock
      2-Thiophenecarboxaldehyde|CS-W013657
      98-03-3

    References

    • Kim, Bo Ram; Lee, Hyung-Geun; Kim, Eun Jung; Lee, Sang-Gyeong; Yoon, Yong-Jin Journal of Organic Chemistry, 2010 , vol. 75, # 2 p. 484 - 486

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302
Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.5606
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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