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2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione

  • CAS No. 959150-64-2

  • Cat. No. CS-0112071
  • Purity≥98%
  • MDL No.MFCD31735040

*For research and further manufacturing use only, not for direct human use.

2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione|CS-0112071

Structure of 959150-64-2

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General Information

  • CAS No. 959150-64-2
  • Cat. No. CS-0112071
  • Purity ≥98%
  • MDL No. MFCD31735040
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉IN₂O₄
  • Molecular Weight 384.13
  • Synonym(s) None
  • SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3I)=O

Description

This isoindoline-1,3-dione derivative features a 4-iodo substituent and a 2-(2,6-dioxopiperidin-3-yl) moiety, enabling efficient coupling in transition-metal-catalyzed transformations. The electron-deficient core supports stable participation in cross-coupling reactions under standard conditions.

Application

2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione serves as a versatile building block for the synthesis of complex heterocyclic scaffolds. The iodine substituent enables palladium-catalyzed cross-coupling reactions, while the isoindoline-1,3-dione core provides a stable, electron-deficient platform for further functionalization. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient access to substituted indolinone derivatives relevant to medicinal chemistry research.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   0.5465
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   1

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