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CS-W001157 4
Total: USD 88.00

Thalidomide 5-fluoride

  • CAS No. 835616-61-0

  • Cat. No. CS-0127616
  • Purity≥97%
  • MDL No.MFCD30188075

*For research and further manufacturing use only, not for direct human use.

Thalidomide 5-fluoride|CS-0127616

Structure of 835616-61-0

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General Information

  • CAS No. 835616-61-0
  • Cat. No. CS-0127616
  • Purity ≥97%
  • MDL No. MFCD30188075
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉FN₂O₄
  • Molecular Weight 276.22
  • Synonym(s) None
  • SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(F)=C3)=O

Description

Thalidomide 5-fluoride features a fluorinated analog of thalidomide, where the 5-position on the phthalimide ring bears a fluorine substituent. This modification enhances metabolic stability and modulates electronic properties, enabling targeted investigation into immunomodulatory and anti-angiogenic mechanisms. The compound retains core biological activity while offering improved pharmacokinetic characteristics for preclinical studies.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H361
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   0.2102
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   1

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