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CS-W001157 4
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6-(Aminomethyl)pyridin-2(1H)-one hydrochloride

  • CAS No. 95878-02-7

  • Cat. No. CS-0119758
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(Aminomethyl)pyridin-2(1H)-one hydrochloride|CS-0119758

Structure of 95878-02-7

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General Information

  • CAS No. 95878-02-7
  • Cat. No. CS-0119758
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉ClN₂O
  • Molecular Weight 160.60
  • Synonym(s) 6-(AMINOMETHYL)PYRIDIN-2(1H)-ONE HCL
  • SMILES O=C1C=CC=C(CN)N1.[H]Cl

Description

6-(Aminomethyl)pyridin-2(1H)-one hydrochloride features a pyridinone core with a pendant aminomethyl group, enabling direct conjugation or metal coordination. This bench-stable derivative delivers enhanced solubility and reactivity in synthetic transformations, particularly useful for constructing bioactive heterocycles and functionalized ligands under standard conditions.

Application

6-(Aminomethyl)pyridin-2(1H)-one hydrochloride serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. The amine-functionalized pyridinone core enables direct incorporation into peptide-like scaffolds, facilitates conjugation reactions, and supports metal coordination in transition-metal catalysis. Bench-stable and readily purified by recrystallization, it exhibits good solubility in polar solvents and tolerates common functional groups, making it ideal for modular library synthesis and API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.88
  • LogP   0.2554
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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