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CS-W001157 4
Total: USD 88.00

2-Ethoxy-5-methoxyphenylboronic acid

  • CAS No. 957065-85-9

  • Cat. No. CS-0151504
  • Purity≥98%
  • MDL No.MFCD09878346

*For research and further manufacturing use only, not for direct human use.

2-Ethoxy-5-methoxyphenylboronic acid|CS-0151504

Structure of 957065-85-9

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General Information

  • CAS No. 957065-85-9
  • Cat. No. CS-0151504
  • Purity ≥98%
  • MDL No. MFCD09878346
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃BO₄
  • Molecular Weight 196.01
  • Synonym(s) 2-Ethoxy-5-methoxyphenyL
  • SMILES CCOC1=C(C=C(C=C1)OC)B(O)O

Description

2-Ethoxy-5-methoxyphenylboronic acid delivers a boronate moiety flanked by electron-donating ethoxy and methoxy groups, enhancing stability and reactivity in Suzuki-Miyaura couplings. This bench-stable reagent integrates readily into complex molecular architectures under standard conditions.

Application

2-Ethoxy-5-methoxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its ortho-ethoxy and meta-methoxy substituents provide enhanced solubility and stability, while the boronic acid functionality offers reliable reactivity under mild conditions. The compound exhibits excellent functional group tolerance and is well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.2263
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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