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CS-W001157 4
Total: USD 88.00

(4-Ethoxy-2,6-dimethylphenyl)boronic acid

  • CAS No. 1315342-15-4

  • Cat. No. CS-0151486
  • Purity≥97%
  • MDL No.MFCD12026736

*For research and further manufacturing use only, not for direct human use.

(4-Ethoxy-2,6-dimethylphenyl)boronic acid|CS-0151486

Structure of 1315342-15-4

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General Information

  • CAS No. 1315342-15-4
  • Cat. No. CS-0151486
  • Purity ≥97%
  • MDL No. MFCD12026736
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅BO₃
  • Molecular Weight 194.04
  • Synonym(s) 4-Ethoxy-2,6-dimethylphenylboronic acid
  • SMILES CCOC1=CC(=C(C(=C1)C)B(O)O)C

Description

This boronate moiety features a sterically hindered aryl scaffold with electron-donating ethoxy and methyl groups, enhancing stability and reactivity in Suzuki-Miyaura couplings. The para-ethoxy substituent improves solubility in organic media while maintaining bench-stable handling under standard conditions.

Application

(4-Ethoxy-2,6-dimethylphenyl)boronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its ortho-methyl groups enhance regiochemical control and improve crystallinity, facilitating purification. The ethoxy substituent provides moderate electron donation, tuning reactivity for efficient coupling with aryl halides and triflates. This boronic acid functions effectively in diverse synthetic workflows requiring robust, functional group-tolerant coupling partners.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.38194
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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