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CS-W001157 4
Total: USD 88.00

(4-Ethoxy-2,5-dimethylphenyl)boronic acid

  • CAS No. 1217500-56-5

  • Cat. No. CS-0100650
  • Purity≥97%
  • MDL No.MFCD12026704

*For research and further manufacturing use only, not for direct human use.

(4-Ethoxy-2,5-dimethylphenyl)boronic acid|CS-0100650

Structure of 1217500-56-5

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General Information

  • CAS No. 1217500-56-5
  • Cat. No. CS-0100650
  • Purity ≥97%
  • MDL No. MFCD12026704
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅BO₃
  • Molecular Weight 194.04
  • Synonym(s) 2,5-Dimethyl-4-ethoxyphenylboronic acid
  • SMILES OB(C1=CC(C)=C(OCC)C=C1C)O

Description

This boronate moiety features a sterically hindered, electron-rich aryl scaffold with enhanced solubility and stability under standard conditions. The ethoxy and methyl substituents collectively improve functional group tolerance and facilitate efficient coupling in Suzuki-Miyaura reactions.

Application

(4-Ethoxy-2,5-dimethylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its aryl boronic acid functionality exhibits excellent bench stability and compatibility with diverse functional groups, facilitating the synthesis of substituted biaryls and complex heterocyclic scaffolds commonly encountered in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.38194
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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