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Structure of 955137-85-6
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trans-1-Boc-4-(4-trifluoromethylphenyl)-pyrrolidine-3-carboxylic acid features a rigid trans-configured pyrrolidine core bearing a Boc-protected amine and a para-trifluoromethylphenyl group. This electron-deficient aryl moiety enhances metabolic stability, while the bench-stable Boc protection simplifies downstream derivatization in peptide and medicinal chemistry workflows.
trans-1-Boc-4-(4-trifluoromethylphenyl)-pyrrolidine-3-carboxylic acid serves as a stable, bench-ready building block for the synthesis of bioactive heterocycles and peptidomimetics. Its trans-configured pyrrolidine core, combined with orthogonal Boc protection and a para-trifluoromethylphenyl group, enables efficient functionalization in standard coupling and reduction reactions. The molecule exhibits excellent stability and facilitates purification via standard chromatographic methods, making it well-suited for iterative medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: