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1-Methyl-1H-indazole-7-carbaldehyde

  • CAS No. 951030-58-3

  • Cat. No. CS-0053909
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-indazole-7-carbaldehyde|CS-0053909

Structure of 951030-58-3

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General Information

  • CAS No. 951030-58-3
  • Cat. No. CS-0053909
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O
  • Molecular Weight 160.17
  • Synonym(s) 1-methylindazole-7-carbaldehyde
  • SMILES O=CC1=CC=CC2=C1N(C)N=C2

Description

1-Methyl-1H-indazole-7-carbaldehyde features a conjugated aldehyde group fused to an electron-rich indazole core, enabling efficient coupling in transition-metal-catalyzed cross-coupling reactions. This bench-stable scaffold integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Application

1-Methyl-1H-indazole-7-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the indazole core via the aldehyde group. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of targeted heterocyclic scaffolds, including those relevant to kinase inhibitors and CNS-active compounds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.89
  • LogP   1.3858
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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