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CS-W001157 4
Total: USD 88.00

5-Amino-1,3-dihydro-2H-benzimidazol-2-one

  • CAS No. 95-23-8

  • Cat. No. CS-W019563
  • Purity≥98%
  • MDL No.MFCD00053555

*For research and further manufacturing use only, not for direct human use.

5-Amino-1,3-dihydro-2H-benzimidazol-2-one|CS-W019563

Structure of 95-23-8

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General Information

  • CAS No. 95-23-8
  • Cat. No. CS-W019563
  • Purity ≥98%
  • MDL No. MFCD00053555
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇N₃O
  • Molecular Weight None
  • Synonym(s) 5-Amino-Benzimidazolone
  • SMILES C1=C(C=CC2=C1NC(N2)=O)N

Description

5-Amino-1,3-dihydro-2H-benzimidazol-2-one is a bench-stable heterocyclic scaffold featuring a fused benzene-imidazolone core with an amino group at the 5-position. This electron-rich moiety serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules via amide coupling or electrophilic substitution reactions under standard conditions.

Synthesis

  • Route1

    References

    • AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara Patent: WO2012/59932 A1, 2012 ; Location in patent: Page/Page column 161-162 ; WO 2012/059932 A1
  • Route2
    • null|null
      99-56-9
    • ~%
    • In-stock
      5-Amino-1,3-dihydro-2H-benzimidazol-2-one|CS-W019563
      95-23-8

    References

    • WO2012/59932 A1, ; WO 2012/059932 A1
  • Route3
    • null|null
      7647-01-0
    • null|null
      35411-68-8
    • ~%
    • In-stock
      5-Amino-1,3-dihydro-2H-benzimidazol-2-one|CS-W019563
      95-23-8

    References

    • Chemische Berichte, , vol. 17, p. 2630

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.67
  • LogP   0.4384
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   0

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