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CS-W001157 4
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(R)-Bis(3,5-bis(trifluoromethyl)phenyl)(pyrrolidin-2-yl)methanol

  • CAS No. 948595-00-4

  • Cat. No. CS-B0073
  • Purity≥97%
  • MDL No.MFCD10566975

*For research and further manufacturing use only, not for direct human use.

(R)-Bis(3,5-bis(trifluoromethyl)phenyl)(pyrrolidin-2-yl)methanol|CS-B0073

Structure of 948595-00-4

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General Information

  • CAS No. 948595-00-4
  • Cat. No. CS-B0073
  • Purity ≥97%
  • MDL No. MFCD10566975
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₅F₁₂NO
  • Molecular Weight 525.33
  • Synonym(s) Bis[3,5-bis(trifluoromethyl)phenyl][(2S)-2-pyrrolidinyl]methanol
  • SMILES OC(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)([C@@H]2NCCC2)C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3

Description

(R)-Bis(3,5-bis(trifluoromethyl)phenyl)(pyrrolidin-2-yl)methanol features a chiral pyrrolidinylmethanol core flanked by two sterically hindered trifluoromethyl-substituted aryl groups. This configuration imparts high stability and distinct electronic properties, enabling precise stereochemical control in asymmetric synthesis. The molecule integrates readily into catalytic systems requiring electron-deficient, bulky ligands.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   6.7497
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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