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CS-W001157 4
Total: USD 88.00

2-(2-Bromo-5-chlorophenyl)ethan-1-ol

  • CAS No. 947614-94-0

  • Cat. No. CS-0142769
  • Purity≥97%
  • MDL No.MFCD20485661

*For research and further manufacturing use only, not for direct human use.

2-(2-Bromo-5-chlorophenyl)ethan-1-ol|CS-0142769

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General Information

  • CAS No. 947614-94-0
  • Cat. No. CS-0142769
  • Purity ≥97%
  • MDL No. MFCD20485661
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BrClO
  • Molecular Weight 235.51
  • Synonym(s) 2-BroMo-5-chloro-benzeneethanol
  • SMILES OCCC1=CC(Cl)=CC=C1Br

Description

2-(2-Bromo-5-chlorophenyl)ethan-1-ol features a brominated and chlorinated aryl core paired with a reactive primary alcohol, enabling direct functionalization in cross-coupling and derivatization workflows. This bench-stable scaffold integrates seamlessly into complex molecular architectures requiring halogen-directed assembly.

Application

2-(2-Bromo-5-chlorophenyl)ethan-1-ol serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant aryl-ethyl scaffolds. Its bromo and chloro substituents offer orthogonal reactivity for palladium-catalyzed cross-coupling and electrophilic substitution, while the primary alcohol facilitates derivatization or protection. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, supporting its utility in multi-step synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.6373
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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