Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-(Trifluoromethyl)-1,3-thiazole-2-carboxylic acid

  • CAS No. 944900-55-4

  • Cat. No. CS-0040379
  • Purity≥98%
  • MDL No.MFCD07377490

*For research and further manufacturing use only, not for direct human use.

4-(Trifluoromethyl)-1,3-thiazole-2-carboxylic acid|CS-0040379

Structure of 944900-55-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 944900-55-4
  • Cat. No. CS-0040379
  • Purity ≥98%
  • MDL No. MFCD07377490
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂F₃NO₂S
  • Molecular Weight 197.14
  • Synonym(s) 4-(Trifluoromethyl)thiazole-2-carboxylic acid
  • SMILES O=C(C1=NC(C(F)(F)F)=CS1)O

Description

4-(Trifluoromethyl)-1,3-thiazole-2-carboxylic acid features a strongly electron-deficient thiazole core augmented by a potent trifluoromethyl group, enhancing both metabolic stability and lipophilicity. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for targeted kinase inhibitors and receptor modulators.

Application

4-(Trifluoromethyl)-1,3-thiazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the thiazole carboxylic acid moiety enables direct coupling reactions for peptide and heterocyclic scaffold construction. The compound exhibits good bench stability, facilitates efficient purification, and functions reliably in standard amide bond formation and Suzuki-Miyaura cross-coupling protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.8601
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 944900-55-4 sigma944900-55-4 manufacturer944900-55-4 price944900-55-4 structure944900-55-4 SDSbuy 944900-55-4944900-55-4 supplier944900-55-4 uses944900-55-4 molecular weightprice of 944900-55-4944900-55-4 chemical name formula of 944900-55-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label