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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoic acid

  • CAS No. 942518-21-0

  • Cat. No. CS-0132617
  • Purity≥96%
  • MDL No.MFCD11052899

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoic acid|CS-0132617

Structure of 942518-21-0

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General Information

  • CAS No. 942518-21-0
  • Cat. No. CS-0132617
  • Purity ≥96%
  • MDL No. MFCD11052899
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₉NO₄
  • Molecular Weight None
  • Synonym(s) Fmoc-L-homopropargylglycine
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCC#C

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoic acid is a chiral, protected amino acid derivative featuring a terminal alkyne handle and a fluorenylmethyl carbamate (Fmoc) group. This combination enables efficient solid-phase peptide synthesis and site-specific conjugation in chemical biology workflows. The electron-rich fluorenyl moiety enhances solubility and stability during purification.

Synthesis

  • Route1
    • null|null
      38771-21-0
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • ~%
    • In-stock
      (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoic acid|CS-0132617
      942518-21-0

    References

    • Kawamoto, Steven A.; Coleska, Adriana; Ran, Xu; Yi, Han; Yang, Chao-Yie; Wang, Shaomeng Journal of Medicinal Chemistry, 2012 , vol. 55, # 3 p. 1137 - 1146

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.3917
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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