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tert-Butyl 3-(1-amino-2-methylpropan-2-yl)-1H-indole-1-carboxylate

  • CAS No. 942148-12-1

  • Cat. No. CS-M0666
  • Molecule weight288.39
  • Purity≥97%
  • MDL No.MFCD18642771

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-(1-amino-2-methylpropan-2-yl)-1H-indole-1-carboxylate|CS-M0666

Structure of 942148-12-1

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General Information

  • CAS No. 942148-12-1
  • Cat. No. CS-M0666
  • Purity ≥97%
  • MDL No. MFCD18642771
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₄N₂O₂
  • Molecular Weight 288.39
  • Synonym(s) 3-(2-Amino-1,1-dimethylethyl)-indole-1-carboxylic acid tert-butyl ester
  • SMILES O=C(OC(C)(C)C)N(C1=CC=CC=C12)C=C2C(C)(C)CN

Synthesis

  • Route1
    • tert-Butyl 3-(2-cyanopropan-2-yl)-1H-indole-1-carboxylate|CS-B0467
      380626-46-0
    • ~%
    • tert-Butyl 3-(1-amino-2-methylpropan-2-yl)-1H-indole-1-carboxylate|CS-M0666
      942148-12-1

    References

    • EXELIXIS, INC. Patent: WO2007/70796 A1, 2007 ; Location in patent: Page/Page column 110; 111; 117-118 ; WO 2007/070796 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   57.25
  • LogP   3.6608
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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