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CS-W001157 4
Total: USD 88.00

1-(Methylamino)butan-2-ol

  • CAS No. 42163-27-9

  • Cat. No. CS-0225521
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(Methylamino)butan-2-ol|CS-0225521

Structure of 42163-27-9

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General Information

  • CAS No. 42163-27-9
  • Cat. No. CS-0225521
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃NO
  • Molecular Weight 103.16
  • Synonym(s) None
  • SMILES CCC(O)CNC

Description

1-(Methylamino)butan-2-ol features a chiral center flanked by a hydroxyl group and a methylamino substituent, delivering enhanced solubility and metabolic stability. This bifunctional scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for targeted ligand design.

Application

1-(Methylamino)butan-2-ol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive amine-containing scaffolds. Its hydroxyl and secondary amine functionalities offer orthogonal reactivity for selective derivatization, while its bench-stable nature facilitates straightforward handling and purification. The molecule functions effectively in standard coupling and protection protocols, supporting efficient access to diverse heterocyclic and peptidomimetic frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.0233
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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