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CS-W001157 4
Total: USD 88.00

1-(Methylamino)propan-2-ol

  • CAS No. 16667-45-1

  • Cat. No. CS-0216704
  • Purity≥98%
  • MDL No.MFCD00089199

*For research and further manufacturing use only, not for direct human use.

1-(Methylamino)propan-2-ol|CS-0216704

Structure of 16667-45-1

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General Information

  • CAS No. 16667-45-1
  • Cat. No. CS-0216704
  • Purity ≥98%
  • MDL No. MFCD00089199
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁NO
  • Molecular Weight 89.14
  • Synonym(s) 1-(methylamino)propan-2-ol HCl
  • SMILES CC(CNC)O

Description

1-(Methylamino)propan-2-ol features a tertiary amine linked to a β-hydroxy scaffold, delivering enhanced solubility and metabolic stability. This structure enables efficient incorporation into bioactive molecules, particularly in medicinal chemistry scaffolds where polarity and hydrogen-bonding capacity are critical.

Application

1-(Methylamino)propan-2-ol serves as a versatile building block in medicinal chemistry, enabling the synthesis of β-amino alcohol scaffolds through standard reductive amination and nucleophilic substitution protocols. Its bench-stable nature, combined with excellent functional group tolerance, facilitates efficient incorporation into diverse heterocyclic systems and peptide-like architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H302+H312-H314-H412
Precautionary Statements : P210-P260-P264-P270-P273-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.4134
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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