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Structure of 940875-99-0
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Ethyl 3-hydrazinylbenzoate hydrochloride features a hydrazinyl group ortho to the ester moiety, enabling direct coupling in heterocycle synthesis. This bench-stable derivative facilitates efficient access to bioactive triazoles and pyrazoles under mild conditions. The hydrochloride salt enhances solubility in polar solvents while maintaining stability during storage.
Ethyl 3-hydrazinylbenzoate hydrochloride serves as a versatile building block for the synthesis of heterocyclic scaffolds, particularly in the construction of quinoxalines and benzimidazoles via condensation with o-dicarbonyl compounds. The hydrazinyl group exhibits robust reactivity under mild conditions, enabling efficient cyclization without requiring stringent anhydrous or inert atmosphere protocols. Its crystalline form ensures ease of handling and purification, while the hydrochloride salt enhances stability during storage and facilitates solubility in common organic solvents. This compound is well-suited for high-throughput medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: