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Structure of 94022-99-8
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This trifluoromethyl-substituted phenylpropanoic acid integrates a robust electron-deficient aryl moiety with a flexible aliphatic carboxylic acid handle, enabling direct conjugation in synthetic routes. The para-trifluoromethyl group enhances metabolic stability and modulates lipophilicity, making this scaffold valuable for medicinal chemistry applications requiring optimized pharmacokinetic profiles.
3-(2-(Trifluoromethyl)phenyl)propanoic acid serves as a valuable building block for bioactive molecule synthesis, featuring a trifluoromethylated aryl group that enhances metabolic stability and membrane permeability. The propionic acid side chain enables straightforward derivatization via esterification, amidation, or coupling reactions. Its bench-stable solid form facilitates handling and purification, making it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P302+P352
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Lot numbers can be found on the outside label of a product: