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CS-W001157 4
Total: USD 88.00

Ethyl 4-methoxybenzoate

  • CAS No. 94-30-4

  • Cat. No. CS-0151752
  • Purity≥97%
  • MDL No.MFCD00015151

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-methoxybenzoate|CS-0151752

Structure of 94-30-4

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General Information

  • CAS No. 94-30-4
  • Cat. No. CS-0151752
  • Purity ≥97%
  • MDL No. MFCD00015151
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) p-Anisic Acid Ethyl Ester
  • SMILES CCOC(=O)C1=CC=C(C=C1)OC

Description

Ethyl 4-methoxybenzoate is a bench-stable ester featuring a para-methoxy-substituted aromatic ring, offering enhanced solubility in organic solvents. This electron-rich moiety enables efficient coupling reactions and serves as a key intermediate in pharmaceutical synthesis and polymer monomer development.

Application

Ethyl 4-methoxybenzoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted aromatic scaffolds. Its ester functionality facilitates nucleophilic acyl substitution, while the para-methoxy group provides predictable electronic activation for electrophilic aromatic substitution. The compound exhibits excellent bench stability and ease of purification, making it well-suited for multi-step synthesis, including transition-metal-catalyzed coupling reactions and heterocycle construction.

Synthesis

  • Route1
    • null|null
      64-17-5
    • null|null
      201230-82-2
    • null|null
      161912-34-1
    • ~92%
    • In-stock
      Ethyl 4-methoxybenzoate|CS-0151752
      94-30-4

    References

    • Organic Letters, , vol. 8, # 22 p. 5161 - 5164
  • Route2
    • null|null
      64-17-5
    • null|null
      201230-82-2
    • In-stock
      4-Iodoanisole|CS-W003965
      696-62-8
    • ~99%
    • In-stock
      Ethyl 4-methoxybenzoate|CS-0151752
      94-30-4

    References

    • Synlett, , # 13 p. 2006 - 2010
  • Route3
    • null|null
      64-17-5
    • 4-Methoxybenzaldehyde, ≥ 99% GC|CS-0676496
      123-11-5
    • ~99%
    • In-stock
      Ethyl 4-methoxybenzoate|CS-0151752
      94-30-4

    References

    • European Journal of Organic Chemistry, , # 8 p. 1144 - 1147

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.8719
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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