Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Chloropropiophenone

  • CAS No. 936-59-4

  • Cat. No. CS-0030740
  • Purity≥98%
  • MDL No.MFCD00000990

*For research and further manufacturing use only, not for direct human use.

3-Chloropropiophenone|CS-0030740

Structure of 936-59-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 936-59-4
  • Cat. No. CS-0030740
  • Purity ≥98%
  • MDL No. MFCD00000990
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉ClO
  • Molecular Weight 168.62
  • Synonym(s) β-Chloroethyl phenyl ketone
  • SMILES O=C(C1=CC=CC=C1)CCCl

Description

3-Chloropropiophenone was used in the asymmetric reduction of (S)-3-chloro-1-phenylpropanol using preheated Candida utilis cells immobilized in calcium alginate gel beads. It was also used in the synthesis of (R)-3-chloro-1-phenyl-1-propanol via asymmetric reduction using in-situ generated oxazaborolidine catalyst derived from (S)-,-diphenylprolinol.

Application

3-Chloropropiophenone serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of pharmaceutically relevant scaffolds. Its α,β-unsaturated ketone functionality supports Michael additions, conjugate reductions, and transition-metal-catalyzed couplings. The chloro substituent enhances electrophilicity for nucleophilic substitution and facilitates downstream functionalization. Bench-stable and amenable to standard purification techniques, it functions reliably in multistep syntheses requiring robust reactivity and predictable transformation pathways.

Synthesis

  • Route1
    • null|null
      625-36-5
    • null|null
      71-43-2
    • ~99%
    • In-stock
      3-Chloropropiophenone|CS-0030740
      936-59-4

    References

    • AARHUS UNIVERSITET; REGION MIDTJYLLAND; JENSEN, Henrik Helligsø; JENSEN, Marie; PETERSEN, Annette L.; SINNING, Steffen; WIBORG, Ove Kjær; NIELSEN, Maja Holch; BOUZINOVA, Elena; OMER, Sahar Patent: WO2013/26455 A1, 2013 ; Location in patent: Page/Page column 74 ;
  • Route2
    • (3-Chloropropyl)benzene Alverine Impurity|CS-0229491
      104-52-9
    • ~97%
    • In-stock
      3-Chloropropiophenone|CS-0030740
      936-59-4

    References

    • Moriyama, Katsuhiko; Takemura, Misato; Togo, Hideo Organic Letters, 2012 , vol. 14, # 9 p. 2414 - 2417
  • Route3
    • null|null
      768-03-6
    • ~88%
    • In-stock
      3-Chloropropiophenone|CS-0030740
      936-59-4

    References

    • Kotani, Shunsuke; Ito, Masaya; Nozaki, Hirono; Sugiura, Masaharu; Ogasawara, Masamichi; Nakajima, Makoto Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6430 - 6433

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.4982
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Chloropropiophenone sigma3-Chloropropiophenone manufacturer3-Chloropropiophenone price3-Chloropropiophenone structure3-Chloropropiophenone SDSbuy 3-Chloropropiophenone3-Chloropropiophenone supplier3-Chloropropiophenone uses3-Chloropropiophenone molecular weightprice of 3-Chloropropiophenone3-Chloropropiophenone chemical name formula of 3-Chloropropiophenone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label