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CS-W001157 4
Total: USD 88.00

3-Chloro-1-(p-tolyl)propan-1-one

  • CAS No. 22422-21-5

  • Cat. No. CS-W017075
  • Molecule weight182.65
  • Purity≥98%
  • MDL No.MFCD00028195

*For research and further manufacturing use only, not for direct human use.

3-Chloro-1-(p-tolyl)propan-1-one|CS-W017075

Structure of 22422-21-5

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General Information

  • CAS No. 22422-21-5
  • Cat. No. CS-W017075
  • Purity ≥98%
  • MDL No. MFCD00028195
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁ClO
  • Molecular Weight 182.65
  • Synonym(s) 4'-Methyl-3-chloropropiophenone
  • SMILES O=C(C1=CC=C(C)C=C1)CCCl

Description

3-Chloro-1-(p-tolyl)propan-1-one features a chlorinated alkyl chain flanked by an aryl and ketone moiety, enabling direct integration into C–C bond-forming reactions. The para-methyl group enhances electron density at the aromatic ring, improving reactivity in nucleophilic additions. This bench-stable ketone serves as a key building block for pharmaceutical intermediates and functionalized polymers under standard conditions.

Synthesis

  • Route1
    • null|null
      108-88-3
    • null|null
      625-36-5
    • ~98%
    • In-stock
      3-Chloro-1-(p-tolyl)propan-1-one|CS-W017075
      22422-21-5

    References

    • Khalaf, Ali A.; Abdel-Wahab, Aboel-Magd A.; El-Khawaga, Ahmed M.; El-Zohry, Maher F. Bulletin de la Societe Chimique de France, 1984 , vol. 2, # 7-8 p. 285 - 291
  • Route2
    • null|null
      108-88-3
    • null|null
      625-36-5
    • ~0%
    • 3-Chloro-1-(o-tolyl)propan-1-one|CS-0551320
      898785-08-5
    • In-stock
      3-Chloro-1-(p-tolyl)propan-1-one|CS-W017075
      22422-21-5

    References

    • Bertolini, Ferruccio; Crotti, Stefano; Di Bussolo, Valeria; Macchia, Franco; Pineschi, Mauro Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 8998 - 9007
  • Route3
    • null|null
      17310-31-5
    • null|null
      625-36-5
    • ~61%
    • In-stock
      3-Chloro-1-(p-tolyl)propan-1-one|CS-W017075
      22422-21-5

    References

    • Khalaf, Ali A.; Abdel-Wahab, Aboel-Magd A.; El-Khawaga, Ahmed M.; El-Zohry, Maher F. Bulletin de la Societe Chimique de France, 1984 , vol. 2, # 7-8 p. 285 - 291

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.80662
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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