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CS-W001157 4
Total: USD 88.00

3-Phenylpyrrolidine

  • CAS No. 936-44-7

  • Cat. No. CS-W002828
  • Purity≥95%
  • MDL No.MFCD01838169

*For research and further manufacturing use only, not for direct human use.

3-Phenylpyrrolidine|CS-W002828

Structure of 936-44-7

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General Information

  • CAS No. 936-44-7
  • Cat. No. CS-W002828
  • Purity ≥95%
  • MDL No. MFCD01838169
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃N
  • Molecular Weight None
  • Synonym(s) 3-Phenylpyrrolidin
  • SMILES C1(C2CCNC2)=CC=CC=C1

Description

3-Phenylpyrrolidine features a rigid, electron-rich pyrrolidine core fused with a phenyl ring, enhancing its structural stability and enabling effective integration into bioactive scaffolds. This bench-stable, moisture-tolerant heterocycle serves as a key building block in medicinal chemistry, particularly for CNS-targeted compounds where conformational restraint improves target affinity and metabolic resilience.

Synthesis

  • Route1
    • tert-Butyl 3-phenylpyrrolidine-1-carboxylate|CS-0154761
      147410-43-3
    • ~86%
    • In-stock
      3-Phenylpyrrolidine|CS-W002828
      936-44-7

    References

    • MITSUBISHI PHARMA CORPORATION; SANOFI-AVENTIS Patent: WO2007/119463 A1, 2007 ; Location in patent: Page/Page column 204; 205 ; WO 2007/119463 A1
  • Route2
    • null|null
      1026-59-1
    • ~89%
    • In-stock
      3-Phenylpyrrolidine|CS-W002828
      936-44-7

    References

    • Roussi, Georges; Zhang, Jidong Tetrahedron, 1991 , vol. 47, # 28 p. 5161 - 5172
  • Route3
    • null|null
      830319-60-3
    • ~90%
    • In-stock
      3-Phenylpyrrolidine|CS-W002828
      936-44-7

    References

    • Evans, Paul; McCabe, Thomas; Morgan, Ben S.; Reau, Sophie Organic Letters, 2005 , vol. 7, # 1 p. 43 - 46

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.7635
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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