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CS-W001157 4
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(4-Ethynylphenyl)methanamine hydrochloride

  • CAS No. 935528-07-7

  • Cat. No. CS-0188480
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-Ethynylphenyl)methanamine hydrochloride|CS-0188480

Structure of 935528-07-7

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General Information

  • CAS No. 935528-07-7
  • Cat. No. CS-0188480
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀ClN
  • Molecular Weight 167.64
  • Synonym(s) (4-ethynylphenyl)methanamine,hydrochloride
  • SMILES C#CC1=CC=C(C=C1)CN.Cl

Description

(4-Ethynylphenyl)methanamine hydrochloride features a terminal alkyne group conjugated to an aromatic ring, enabling efficient copper-catalyzed coupling reactions. The protonated amine enhances solubility in aqueous and polar organic media, simplifying handling in synthetic workflows. This bench-stable derivative serves as a key building block for bioconjugation and materials chemistry applications.

Application

(4-Ethynylphenyl)methanamine hydrochloride serves as a versatile building block for the synthesis of functionalized arylacetylenes and conjugated heterocycles. Its terminal alkyne group enables efficient copper-catalyzed coupling reactions, while the primary amine functionality facilitates facile derivatization. The hydrochloride salt enhances bench stability and simplifies purification, making it well-suited for use in medicinal chemistry and materials science applications requiring precise structural control.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.5484
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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