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CS-W001157 4
Total: USD 88.00

3-(Furan-2-yl)propanoic acid

  • CAS No. 935-13-7

  • Cat. No. CS-0155529
  • Purity≥98%
  • MDL No.MFCD00005346

*For research and further manufacturing use only, not for direct human use.

3-(Furan-2-yl)propanoic acid|CS-0155529

Structure of 935-13-7

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General Information

  • CAS No. 935-13-7
  • Cat. No. CS-0155529
  • Purity ≥98%
  • MDL No. MFCD00005346
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈O₃
  • Molecular Weight 140.14
  • Synonym(s) furan-2-propionic acid
  • SMILES C1=COC(=C1)CCC(=O)O

Description

This furan-containing carboxylic acid integrates a conjugated heterocyclic moiety with a flexible aliphatic chain, enabling efficient incorporation into bioactive scaffolds. The para-substituted furan ring enhances electron delocalization, while the pendant acid group facilitates derivatization under standard coupling conditions.

Application

3-(Furan-2-yl)propanoic acid serves as a versatile building block for heterocyclic synthesis and bioactive molecule development. Its conjugated furan–alkyl chain enables efficient Michael additions, electrophilic substitutions, and transition-metal-catalyzed couplings. The carboxylic acid functionality offers direct access to esters, amides, and acyl chlorides, facilitating downstream derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in standard organic transformations and is well-suited for medicinal chemistry lead optimization.

Synthesis

  • Route1
    • 3-(Furan-2-yl)acrylic acid Nalfurafine  Impurity|CS-0229198
      539-47-9
    • ~91%
    • In-stock
      3-(Furan-2-yl)propanoic acid|CS-0155529
      935-13-7

    References

    • Kassianidis, Eleftherios; Pearson, Russell J.; Philp, Douglas Chemistry - A European Journal, 2006 , vol. 12, # 34 p. 8798 - 8812
  • Route2

    References

    • Schelkun, Robert M.; Yuen, Po-Wai; Wustrow, David J.; Kinsora, Jack; Su, Ti-Zhi; Vartanian, Mark G. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 9 p. 2329 - 2332
  • Route3
    • 2-(2-Chloroethyl)furan|CS-1161293
      63825-24-1
    • ~%
    • In-stock
      3-(Furan-2-yl)propanoic acid|CS-0155529
      935-13-7

    References

    • Journal of the American Chemical Society, , vol. 63, p. 206

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.44
  • LogP   1.2968
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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