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Structure of 934554-41-3
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8-Chloroisoquinolin-5-amine features a chlorinated isoquinoline core with a strategically positioned primary amine at the 5-position, enabling direct functionalization in synthetic transformations. This electron-deficient heterocycle serves as a key scaffold for pharmaceutical intermediates and ligand development.
8-Chloroisoquinolin-5-amine serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient access to isoquinoline-based scaffolds. Its ortho-chloro and amine functionalities support sequential functionalization via palladium-catalyzed cross-coupling and electrophilic substitution. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative library synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: