(2-Bromo-4-methylthiazol-5-yl)methanol

Name: (2-Bromo-4-methylthiazol-5-yl)methanol
Brand: ChemScene
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CAS No. 933782-03-7
Cat. No. CS-0162332
Purity≥98%
MDL No.MFCD20441256

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(2-Bromo-4-methylthiazol-5-yl)methanol|CS-0162332

Structure of 933782-03-7

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Description

This bromomethylthiazole derivative features a reactive methanol group flanked by an electron-deficient thiazole ring and a methyl substituent. It serves as a key intermediate in the synthesis of bioactive heterocycles, offering enhanced stability and selective functionalization under standard conditions.

Application

(2-Bromo-4-methylthiazol-5-yl)methanol serves as a versatile building block for thiazole-based scaffolds, enabling efficient functionalization via nucleophilic substitution and cross-coupling reactions. The bromo group facilitates palladium-catalyzed transformations, while the pendant alcohol supports derivatization or protection strategies. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for medicinal chemistry and process development workflows.

General Information

CAS No. 933782-03-7
Cat. No. CS-0162332
Purity ≥98%
MDL No. MFCD20441256
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₆BrNOS
Molecular Weight 208.08
Synonym(s) JR-13435, (2-Bromo-4-methylthiazol-5-yl)methanol
SMILES OCC1=C(C)N=C(Br)S1

Computational Chemistry Data

TPSA 33.12
LogP 1.70632
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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(2-Bromo-4-methylthiazol-5-yl)methanol

CAS No. 933782-03-7

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