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Structure of 933755-97-6
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1-Ethynylcyclopropanecarboxylic acid features a strained cyclopropyl ring fused to an ethynyl and carboxylic acid group, enabling direct access to functionalized cyclopropyl architectures. The acetylenic handle facilitates efficient copper-catalyzed coupling reactions, while the acidic proton supports derivatization under mild conditions. This compound serves as a versatile scaffold for probing bioactive molecular motifs in medicinal chemistry and materials synthesis.
1-Ethynylcyclopropanecarboxylic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized cyclopropyl scaffolds via transition-metal-catalyzed coupling reactions. Its terminal alkyne functionality facilitates Sonogashira and Huisgen cycloadditions, while the carboxylic acid group supports direct derivatization or activation for peptide and macrocycle synthesis. The molecule exhibits excellent bench stability and is compatible with a range of protecting groups, making it well-suited for modular library construction and medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: