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Structure of 933724-95-9
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This thiazole-containing carboxylic acid integrates a rigid, electron-deficient heterocycle with a flexible aliphatic chain, enabling robust conjugation in bioactive molecule design. The para-positioned thiazole enhances metabolic stability and modulates lipophilicity for improved membrane permeability. This scaffold serves as a key building block in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.
3-(Thiazol-5-yl)propanoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its thiazole moiety provides robust metabolic stability and favorable pharmacophore characteristics, while the pendant carboxylic acid enables straightforward derivatization via amide, ester, or acyl chloride formation. The compound exhibits good bench stability and is compatible with standard coupling reactions, facilitating efficient incorporation into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: