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Structure of 93224-07-8
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5-(Bromomethyl)pyrimidine hydrobromide delivers a reactive bromomethyl handle at the 5-position of pyrimidine, enabling efficient coupling in nucleophilic substitution reactions. The hydrobromide salt enhances solubility and stability in polar solvents, facilitating use in synthetic workflows requiring controlled reactivity. This compound serves as a key intermediate for functionalizing heterocyclic systems.
5-(Bromomethyl)pyrimidine hydrobromide serves as a versatile building block for pyrimidine-based scaffolds, enabling efficient functionalization at the 5-position via nucleophilic substitution. Its bromomethyl group exhibits high reactivity in SN2 reactions, facilitating the introduction of diverse substituents under mild conditions. The compound demonstrates excellent bench stability and compatibility with common protecting groups, making it well-suited for iterative synthesis in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: