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CS-W001157 4
Total: USD 88.00

DMT-dG(ib) Phosphoramidite

  • CAS No. 93183-15-4

  • Cat. No. CS-W009564
  • Purity≥95%
  • MDL No.MFCD00055147

*For research and further manufacturing use only, not for direct human use.

DMT-dG(ib) Phosphoramidite|CS-W009564

Structure of 93183-15-4

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General Information

  • CAS No. 93183-15-4
  • Cat. No. CS-W009564
  • Purity ≥95%
  • MDL No. MFCD00055147
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₄H₅₄N₇O₈P
  • Molecular Weight 839.92
  • Synonym(s) None
  • SMILES COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@H](N5C(N=C(NC(C(C)C)=O)NC6=O)=C6N=C5)O4

Description

DMT-dG(ib) Phosphoramidite delivers a protected guanine nucleoside with a dimethoxytrityl (DMT) group at the 5′-position and an isobutyryl (ib) modification on the exocyclic amine. This derivative enables efficient incorporation into oligonucleotide synthesis, offering enhanced stability and simplified deprotection. The DMT group provides robust UV monitoring during synthesis, while the ib protection ensures high fidelity in automated workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   175.08
  • LogP   7.68868
  • H_Acceptors   13
  • H_Donors   2
  • Rotatable_Bonds   19

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