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CS-W001157 4
Total: USD 88.00

1,2-Cyclohexanediol

  • CAS No. 931-17-9

  • Cat. No. CS-0155355
  • Purity≥95%
  • MDL No.MFCD00003861

*For research and further manufacturing use only, not for direct human use.

1,2-Cyclohexanediol|CS-0155355

Structure of 931-17-9

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General Information

  • CAS No. 931-17-9
  • Cat. No. CS-0155355
  • Purity ≥95%
  • MDL No. MFCD00003861
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₂
  • Molecular Weight 116.16
  • Synonym(s) 1,2-Dihydroxycyclohexane (cis- and trans- mixture)
  • SMILES C1CCC(C(C1)O)O

Description

1,2-Cyclohexanediol offers a rigid, vicinal diol architecture ideal for stereocontrolled transformations. This bench-stable compound features high solubility in polar solvents and serves as a reliable chiral synthon in asymmetric synthesis. The adjacent hydroxyl groups enable efficient derivatization through oxidation, protection, or cyclization reactions.

Application

1,2-Cyclohexanediol serves as a versatile diol building block in synthetic organic chemistry, enabling stereoselective transformations through its well-defined cis-configuration. Its bench-stable nature and compatibility with common protecting group strategies facilitate efficient functionalization in complex molecule synthesis. The compound functions effectively in oxidation, acetal formation, and coupling reactions, supporting applications in natural product synthesis and pharmaceutical intermediate development.

Synthesis

  • Route1
    • null|null
      110-83-8
    • ~26%
    • null|null
      930-68-7
    • In-stock
      1,2-Cyclohexanediol|CS-0155355
      931-17-9

    References

    • Journal of Molecular Catalysis A: Chemical, , vol. 379, p. 340 - 349
  • Route2
    • null|null
      110-83-8
    • ~96%
    • In-stock
      1,2-Cyclohexanediol|CS-0155355
      931-17-9

    References

    • Malla Reddy; Srinivasulu; Venkat Reddy; Narasimhulu; Venkateswarlu Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5285 - 5288
  • Route3
    • null|null
      120-80-9
    • ~%
    • In-stock
      1,2-Cyclohexanediol|CS-0155355
      931-17-9
    • null|null
      108-94-1
    • In-stock
      1-Cyclohexanol|CS-0017198
      108-93-0

    References

    • Applied Catalysis A: General, , vol. 466, p. 21 - 31

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.2822
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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