7-Chloropyrido[3,4-b]pyrazine

Name: 7-Chloropyrido[3,4-b]pyrazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 93049-39-9
Cat. No. CS-0097873
Purity≥97%
MDL No.MFCD11044722

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Chloropyrido[3,4-b]pyrazine|CS-0097873

Structure of 93049-39-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 93049-39-9
Cat. No. CS-0097873
Purity ≥97%
MDL No. MFCD11044722
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄ClN₃
Molecular Weight 165.58
Synonym(s) PYRIDO[3,4-B]PYRAZINE, 7-CHLORO-
SMILES ClC1=NC=C(N=CC=N2)C2=C1

Description

7-Chloropyrido[3,4-b]pyrazine is a heteroaromatic scaffold featuring a chlorinated pyridopyrazine core. This electron-deficient system integrates readily into medicinal chemistry campaigns, offering a rigid, planar framework for kinase inhibitor design. The chlorine substituent enhances binding affinity through dipole interactions and contributes to metabolic stability in biological assays.

Application

7-Chloropyrido[3,4-b]pyrazine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its electron-deficient pyridopyrazine core enables efficient transition metal-catalyzed coupling reactions, particularly in Suzuki-Miyaura and Buchwald-Hartwig protocols. The chlorine substituent provides a reliable handle for nucleophilic displacement, facilitating the installation of diverse aryl, heteroaryl, and amine functionalities under mild conditions. Bench-stable and readily purified by flash chromatography, it functions effectively in multi-step synthesis of kinase inhibitors and other bioactive scaffolds.

Synthesis

Route1
- In-stock
  
  89182-17-2
- 131543-46-9
- ~%
- In-stock
  
  93049-39-9
References
- WO2010/52448 A2, ; Page/Page column 73 ; WO 2010/052448 A2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 38.67
LogP 1.6782
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

7-Chloropyrido[3,4-b]pyrazine sigma7-Chloropyrido[3,4-b]pyrazine manufacturer7-Chloropyrido[3,4-b]pyrazine price7-Chloropyrido[3,4-b]pyrazine structure7-Chloropyrido[3,4-b]pyrazine SDSbuy 7-Chloropyrido[3,4-b]pyrazine7-Chloropyrido[3,4-b]pyrazine supplier7-Chloropyrido[3,4-b]pyrazine uses7-Chloropyrido[3,4-b]pyrazine molecular weightprice of 7-Chloropyrido[3,4-b]pyrazine7-Chloropyrido[3,4-b]pyrazine chemical name formula of 7-Chloropyrido[3,4-b]pyrazine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

7-Chloropyrido[3,4-b]pyrazine

CAS No. 93049-39-9

Recommended Products